Information for
members of the general public

Hereditary angioedema (HAE)

HAE is a rare condition caused by a deficiency or dysfunction of an important protein found in the blood known as C1 esterase inhibitor (C1-INH).1–3

People with HAE can experience swelling in certain parts of their body, such as the stomach, hands, and face. The swelling can be painful, and in some cases, life-threatening.1-3 An episode of swelling is referred to as an ‘attack’.

HAE is a genetic condition, meaning it runs in families.3 There is currently no cure for HAE, but people with the condition can still lead a full and active life.

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REFERENCES

  1. Craig TJ, et al. J Allergy Clin Immunol 2011; 66: 1604–1112
  2. Gompels MM, et al. Clin Exp Immunol 2005; 139: 379–394
  3. Longhurst HJ, et al. Clin Exp Immunol. 2015; 180(3): 475–483